Literature
Effects of SGLT2 inhibition on incident heart failure in carriers of cardiomyopathy-associated genetic variants.
Effects of SGLT2 inhibition on incident heart failure in carriers of cardiomyopathy-associated genetic variants.: New evidence identified. See linked sources for details.
These results need to be confirmed in a prospective, dedicated trial of preventive HF treatments in carriers of P/LP cardiomyopathy-associated variants.
Relevance: Study on SGLT2 inhibition (dapagliflozin) and heart failure prevention in carriers of cardiomyopathy-associated genetic variants. Directly relevant to heart failure research interest and pharmacological management. Although in adult population, findings on HF prevention in genetic cardiomyopathy carriers inform pediatric practice with similar underlying genetic conditions.
PMID: 42260102Nature medicine(Journal Article) Literature
Escalation to transplantation in refractory stone heart syndrome: a case report of advanced mechanical circulatory support failure.
Escalation to transplantation in refractory stone heart syndrome: a case report of advanced mechanical circulatory support failure.: New evidence identified. See linked sources for details.
In cases of irreversible global myocardial injury, orthotopic heart transplantation remains the only curative treatment option.
Relevance: Case report of stone heart syndrome complication after cardiac surgery requiring heart transplantation. Related to acute heart failure and post-operative cardiac complications in a young patient, but stone heart is a specific rare complication not directly matching profile diagnoses.
PMID: 42304518Journal of cardiothoracic surgery(Case Reports)