Literature
Clinical, hemodynamic, and safety outcomes of sotatercept in pulmonary arterial hypertension: a meta-analysis of randomized trials with time-to-event data.
Clinical, hemodynamic, and safety outcomes of sotatercept in pulmonary arterial hypertension: a meta-analysis of randomized trials with time-to-event data.: New evidence identified. See linked sources for details.
PROSPERO ID: CRD420251166414.
Relevance: Meta-analysis of sotatercept efficacy in pulmonary arterial hypertension (PAH), a key research interest. Demonstrates novel therapeutic approach for pulmonary hypertension with hemodynamic and clinical outcomes data relevant to management of profile diagnoses (Fontan, TOF, TGA) that commonly develop PAH.
PMID: 42312805Therapeutic advances in respiratory disease(Journal Article) Literature
Gastrointestinal bleeding risk among antithrombotics users: a propensity score matched study of drug classes.
Gastrointestinal bleeding risk among antithrombotics users: a propensity score matched study of drug classes.: New evidence identified. See linked sources for details.
The protocol (STUDY00016941) was reviewed and received exemption determination by the University of Minnesota Institutional Review Board.
Relevance: Study examining gastrointestinal bleeding risk with antithrombotic agents including warfarin (drug-warfarin). Directly relevant to warfarin safety profile in adult populations, which informs pediatric anticoagulation practice. Addresses anticoagulation safety, a core research interest.
PMID: 42249767Expert opinion on drug metabolism & toxicology(Journal Article) Literature
Guide from the Colegio Mexicano de Reumatología for the Pharmacological Treatment of Systemic Sclerosis Part 1: Cutaneous Involvement, Interstitial Lung Disease, and Pulmonary Arterial Hypertension.
Guide from the Colegio Mexicano de Reumatología for the Pharmacological Treatment of Systemic Sclerosis Part 1: Cutaneous Involvement, Interstitial Lung Disease, and Pulmonary Arterial Hypertension.: New evidence identified. See linked sources for details.
A total of 26 recommendations were issued and subjected to Delphi consensus, with agreement defined as ≥80% acceptance.
Relevance: Guideline on pharmacological treatment of systemic sclerosis with discussion of pulmonary arterial hypertension management. While PAH is a research interest, this is limited to adult systemic sclerosis context rather than congenital heart disease. Tangentially related through PAH discussion.
PMID: 42270533Reumatologia clinica(Journal Article)