Literature
Heart Failure Medication Withdrawal in Patients With Improved Cardiac Function After Atrial Fibrillation Ablation: The DEFINITION-AF Pilot Randomized Clinical Trial.
Heart Failure Medication Withdrawal in Patients With Improved Cardiac Function After Atrial Fibrillation Ablation: The DEFINITION-AF Pilot Randomized Clinical Trial.: New evidence identified. See linked sources for details.
Chinese Clinical Trial Registry Identifier: ChiCTR2300077439.
Relevance: Randomized trial of heart failure medication (GDMT) withdrawal in adult patients with improved cardiac function after AF ablation. Directly relevant to profile research interest in heart failure management and profile drugs (ACE inhibitors, beta-blockers); findings inform medication optimization strategies applicable to pediatric heart failure.
PMID: 42360743JAMA network open(Journal Article) Literature
Hepatic artery aneurysm rupture into the biliary tract during long-term left ventricular assist device support successfully treated by transcatheter arterial embolization: a case report.
Hepatic artery aneurysm rupture into the biliary tract during long-term left ventricular assist device support successfully treated by transcatheter arterial embolization: a case report.: New evidence identified. See linked sources for details.
Prompt multidisciplinary management and endovascular intervention are essential for favorable outcomes.
Relevance: Case report of bleeding complication in adult on long-term LVAD support with anticoagulation therapy. Related to profile drug warfarin (anticoagulation in advanced heart failure) and relevant to understanding anticoagulation complications, though in adult advanced HF rather than pediatric population.
PMID: 42365213Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs(Journal Article) Literature
Observational multicentre registry to update key interventions and new approaches with artificial intelligence for heart failure (OKINAWA-HF): a retrospective medical record-derived registry study protocol.
Observational multicentre registry to update key interventions and new approaches with artificial intelligence for heart failure (OKINAWA-HF): a retrospective medical record-derived registry study protocol.: New evidence identified. See linked sources for details.
We will also conduct dissemination events to report the study findings and support their application in regional clinical practices.
Relevance: Registry protocol for studying guideline-directed medical therapy implementation in adult heart failure. Related to profile research interest in heart failure and profile drugs; addresses real-world medication optimization relevant to pediatric HF management.
PMID: 42350022BMJ open(Journal Article) Literature
Determinants of Adherence to a Ketogenic Diet in Patients with Heart Failure with Reduced Ejection Fraction.
Determinants of Adherence to a Ketogenic Diet in Patients with Heart Failure with Reduced Ejection Fraction.: New evidence identified. See linked sources for details.
These findings highlight the need for improved education, support, and increased food options to optimise implementation of dietary ketosis in HF.
Relevance: Qualitative study of adherence to ketogenic diet in adult heart failure with reduced ejection fraction. Related to profile research interest in heart failure but focuses on dietary intervention rather than pharmacologic or surgical management specific to pediatric cardiac diagnoses.
PMID: 42356244Nutrients(Journal Article) Literature
Health Status Changes and Long-Term Clinical Outcomes in Patients With Atrial Fibrillation.
Health Status Changes and Long-Term Clinical Outcomes in Patients With Atrial Fibrillation.: New evidence identified. See linked sources for details.
These findings support the prognostic value of PROMs and highlight the importance of monitoring health status in AF management.
Relevance: Cohort study evaluating association between patient-reported health status changes and long-term outcomes in adult atrial fibrillation patients. Directly relevant to heart failure and arrhythmia management; findings on outcomes monitoring and quality of life assessment inform pediatric cardiac follow-up strategies.
PMID: 42295760JAMA network open(Journal Article) Literature
Comparison of clinical outcomes of enoxaparin and aspirin for postoperative venous thromboembolism prophylaxis in hip fractures.
Comparison of clinical outcomes of enoxaparin and aspirin for postoperative venous thromboembolism prophylaxis in hip fractures.: New evidence identified. See linked sources for details.
2026; 60(2), 0305, doi: 10.5152/j.aott.2026.25305.
Relevance: Comparison of aspirin and enoxaparin for venous thromboembolism prophylaxis in adult hip fracture patients. Directly relevant to profile drug aspirin and anticoagulation principles, though in adult orthopedic population rather than pediatric cardiac patients. Findings on aspirin efficacy and safety inform pediatric anticoagulation practice.
PMID: 42364203Acta orthopaedica et traumatologica turcica(Journal Article) Literature
Pregnancy-related adverse events and congenital disorders associated with aspirin: A real-world pharmacovigilance analysis of the FDA adverse event reporting system.
Pregnancy-related adverse events and congenital disorders associated with aspirin: A real-world pharmacovigilance analysis of the FDA adverse event reporting system.: New evidence identified. See linked sources for details.
this large-scale pharmacovigilance study identified significant disproportionality signals for several pregnancy-related AEs and congenital disorders reported with aspirin use. While these findings provide preliminary signals...
Relevance: Pharmacovigilance study of aspirin-associated pregnancy-related adverse events and congenital disorders. Related to profile drug aspirin but focuses on obstetric population and congenital anomalies rather than pediatric cardiac disease management or heart failure treatment.
PMID: 42363462Medicine(Journal Article)